A scientific breakthrough may give many women suffering
from breast
cancer a new ray of hope after a group of researchers at the University
of Basel in Switzerland said that they have successfully transformed breast
cancer cells into fat — “rendering them harmless, and stopping the disease from
moving to other parts of the body.
The researchers took mice implanted with an aggressive form
of human breast cancer, and treated them with both a diabetic drug called
rosiglitazone and a cancer treatment called trametinib. The team said they
exploited a weird pathway that metastasizing cancer cells have. When one cuts
their finger, or when a foetus grows organs, the epithelium cells begin to look
less like themselves, and more ‘fluid’ – changing into a type of stem cell
called a mesenchyme and then reforming into whatever cells the body needs.
This process is called epithelial-mesenchymal transition
(EMT) and it’s been known for a while that cancer
can use both this and the opposite pathway called MET
(mesenchymal-to-epithelial transition), to spread throughout the body and metastasize.
When cancer cells used one of the above-mentioned transition pathways, instead
of spreading, they changed from cancer into fat cells – a process called
adipogenesis.
For more details please follow the link: https://frontiersmeetings.com/conferences/breastcancercongress/
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