Vigilance needed to Survive Breast cancer

#Breast_cancer is the most frequently occurring #cancer in women and the second most common cancer globally. Globally, more than two million new cases of breast cancer were reported in 2018. It’s estimated that about 7% of all breast cancer cases diagnosed occur in women under the age of 40. According to the American Cancer Society, about one in eight invasive breast cancers develop in women younger than 45, whereas two in three invasive breast cancers occur in #women aged 55 or older. Breast cancer occurrence also differs between patients diagnosed before and after menopause. Although breast cancer may occur in men, its occurrence is rare, and one in a thousand men may be diagnosed with breast cancer in their lifetime.

Breast cancer is regarded as a #heterogeneous disease — the way it develops and affects individual patients varies greatly. Some breast cancer subtypes are #hormone-dependent. Breast cancer cells that possess #oestrogen receptors are defined as oestrogen-positive (ER+). #Breast_cancer cells containing progesterone receptors are called progesterone-positive (PR+) cancers. Hormone receptor-positive cancers occur more frequently. Hormone receptor-positive cancers also have improved prognosis. Hormone receptor-negative cancers may be more difficult to treat, and have the likelihood of a higher pathological grade.

Preventative surgery may decrease the risk of breast cancer, but does not provide a 100% certainty that the person will not develop cancer. Frequent surveillance and screenings should be considered. #Medication as preventative therapy may also be considered to assist high-risk women to decrease their risk of being diagnosed with cancer. The elimination of #cancer requires a combination of cancer awareness to address the burden of this disease — prevention strategies, contributing to early detection and promoting health and well-being education and the acceleration of science and discovery and progress in technology.

For more details please follow the link: https://frontiersmeetings.com/conferences/breastcancercongress/   

For queries and details contact us: breastcancer@globalbreastcancercongress.org   

#Breast_Cancer_congress_2020  #Zurich #Switzerland #June15-17_2020 #Breast #cancer #Awareness #october #Breast_cancer #Immunotherapy #chemotherapy #Tumor #Breast_Surgery #mastectomy #carcinoma #Breast_conference #Keynote #Oral_sessions

Breast Cancer Awareness: Different types of breast cancer

Globally Breast cancer is the most common type of #cancer in #women. All breast cancers are not the same, they vary, depending on whether they are #invasive which spread to surrounding areas or non-invasive contained in a particular area and a single #tumour or multifocal i.e. multiple tumours.

Triple-negative breast cancer

Each cell in our body has #receptors that link to proteins and other things to perform everyday functions. Research shows that three different kinds of receptors fuel the growth of most #breast_cancers which are estrogen receptors, #progesterone receptors and HER receptors. While estrogen and progesterone are female #hormones, HER-2 is a gene that produces growth proteins - cancer cells can use these proteins to grow.

None of these receptors plays a role in triple-negative breast cancer. This is a problem because this type of #cancer does not respond to the most common breast cancer treatments: first, hormone therapy which suppresses the function of both estrogen and progesterone receptors, and second, drugs that target the growth protein made by the HER-2 gene.

Medullary breast cancer

A rare but invasive type of #cancer that begins in the milk ducts (ductal carcinoma), it is so named because the affected tissues look soft and fleshy like the medulla in the #brain. Medullary #breast_cancer accounts for only 3-5% of the total breast cancer cases and mostly affects women in their 40s and 50s. It spreads slowly but does not affect any tissue outside the breast. It has a good prognosis - there’s a good chance that it can be treated.

Paget’s disease of the breast

Paget’s disease mostly affects the skin of the areola - the dark area surrounding the nipples. To make a diagnosis, doctors look for large cells, called #Paget’s cells, in the affected area. However, most patients also have one or more #tumours inside their breasts. Paget’s disease accounts for 1-4% of all breast cancer cases. Paget’s can affect women of all ages, from young teens to those in their 80s.

Basal-like breast cancer

This cancer gets its name from the fact that it shows up on the basal layer of the milk ducts in tests. It mostly affects younger women (below 40 years of age) and has a poor #prognosis.This type of breast cancer is often confused with #triple_negative_breast_cancer as it often doesn’t have any of the three breast cancer receptors. According to the Canadian Cancer Society, not all basal-like breast cancers are triple-negative. Also, basal cell type cancer has certain changes in proteins that are not seen in triple-negative type.

For more details please follow the link: https://frontiersmeetings.com/conferences/breastcancercongress/   

For queries and details contact us: breastcancer@globalbreastcancercongress.org  

#Breast_Cancer_congress_2020 #Zurich #Switzerland #June15-17_2020 #Breast #cancer #Awareness #October #Breast_cancer #Immunotherapy #chemotherapy #Tumor #Breast_Surgery #mastectomy #carcinoma #Breast_conference #Keynote #Oral_sessions

Breast cancer vaccine

Vaccines, also called vaccinations, are medicines that help the body fight disease. They can train the immune system to recognize and destroy harmful substances. There are 2 types of cancer vaccines: Prevention vaccines & Treatment vaccines. Cancer treatment vaccines, also called therapeutic vaccines, are a type of immunotherapy. The vaccines work to boost the body's natural defenses to fight a cancer. Doctors give treatment vaccines to people already diagnosed with cancer. The vaccines may: 

• Prevent the cancer from coming back
• Destroy any cancer cells still in the body after other treatments have ended
• Stop a tumor from growing or spreading

Cancer treatment vaccines boost the immune system's ability to recognize and destroy antigens. Often, cancer cells have certain molecules called cancer-specific antigens on their surface that healthy cells do not have. When these molecules are given to a person, the molecules act as antigens. They stimulate the immune system to recognize and destroy cancer cells that have these molecules on their surface. Most cancer vaccines also contain adjuvants, which are substances that may help strengthen the immune response.

Some cancer vaccines are made for individual patients. These types of vaccines are produced from the person's tumor sample. This means that surgery is needed to get a large enough sample of the tumor to create the vaccine. Other cancer vaccines target specific cancer antigens and are given to people whose tumors have those antigens on the surface of the tumor cells.

Clinical trials of an immunotherapy treatment for breast cancer showed positive signs, and the researchers hope to move to larger trials in coming years. Immunotherapies train the body's immune system to find and kill cancer cells without harming healthy cells. Recent trials of immunotherapies for other cancers have also showed positive signs. A vaccine that prevents the recurrence and development of breast and ovarian cancers could become available in less than a decade, according to researchers at the Mayo Clinic in Jacksonville, Florida. The researchers developed an immunotherapy treatment that trains the immune system to recognize and kill breast cancer cells. Based on the results of early-stage clinical trials, the vaccine seems to have successfully removed cancer cells in one patient, and another is showing positive results. Mayo Clinic immunologists have also developed two other cancer vaccines for Triple Negative Breast Cancer and HER2 Positive Breast Cancer.

Since the 1990s, immunotherapies have increasingly become an area of interest among medical researchers who seek to defeat cancer without simultaneously destroying healthy cells in the body, as chemotherapy and radiation does. Immunotherapy is, in theory, is the ideal solution. But one major obstacle is that all cancers are different, so it's unclear when or whether immunotherapies will be able to treat the more than 100 types of cancer currently known to scientists. Still, researchers are currently exploring a variety of immunotherapies, and the global immunotherapy drug market is expected to grow to a valuation of $101.6 billion by 2023.

For more details please follow the link: https://frontiersmeetings.com/conferences/breastcancercongress/  

For queries and details contact us: breastcancer@globalbreastcancercongress.org

#Breast_Cancer_congress_2020 #Zurich #Switzerland #June15-17_2020 #Breast #cancer #Awareness #october #Breast_cancer #Immunotherapy #chemotherapy #Tumor #Breast_Surgery #mastectomy #carcinoma #Breast_conference #Keynote #Oral_sessions

Ignorance of Breast cancer signs

Breast cancer awareness!

The month of #October is globally observed as #Breast #Cancer #Awareness month. It is the most commonly present cancer among women, with over 2 million cases increasing every year, according to the World #Cancer_Research Fund.

Symptoms and signs of breast cancer!

Awareness and education can save many lives. Signs, found out early on, can help nip out #breast_cancer, like any other kind of cancer. Early warning #signs and preventive steps like these are essential for survival. While it is a crucial step to go for regular screenings, checkups, the truth is, people won't always know what breast cancer can look like. The signs vary and different people exhibit different symptoms.

Skin dimpling!

#Skin_dimpling is a less common sign of cancer but according to #doctors, this is one step no person should miss out on while checking for signs. A rash or a scab that can cause the skin to turn red, itchy and flaky is a sign of skin dimpling. In some cases, a severe form of skin dimpling or infection can also lead to swelling and thickening of the skin around the breasts, also accompanied by skin pits and inversion or retraction of the nipple.

Skin turning red or orange?

An abnormal #lump, leaky discharge or swelling isn't the only sign pointing to trouble. Another sign which people often ignore is skin dimpling.

Breast Cancer signs!

If your skin dimpling is accompanied by other signs like these, attend to it immediately

·        Swelling and warmness in and around the breast

·        #Breast_tenderness

·        Pain in the affected breast

·        Burning sensation or prickly feeling

·        Reddish, darkened appearance on either of the breasts

For more details please follow the link: https://frontiersmeetings.com/conferences/breastcancercongress/  

For queries and details contact us: breastcancer@globalbreastcancercongress.org

#Breast_Cancer_congress_2020 #Zurich #Switzerland #June15-17_2020 #Breast #cancer #Awareness #october #Breast_cancer #Immunotherapy #chemotherapy #Tumor #Breast_Surgery #mastectomy #carcinoma #Breast_conference #Keynote #Oral_sessions